Sanpanino

For a consistently good sandwich, try Sanpanino in the West Village.  Although they have other bread to choose from, you have to go with the uber-thick slices of focaccia.  I had the San Classico (sopressata, mortadella, fresh mozzarella, roasted peppers, fresh basil, olive oil, and balsamic) grilled and could taste every single ingredient.  It also happens to be filling, so my $7.95 went a long way...half for lunch and half as an afternoon snack.

http://www.menupages.com/restaurants/sanpanino/menu